Angelman syndrome

Key facts Angelman syndrome is a genetic condition that occurs if a gene called UBE3A is missing or faulty. People with Angelman syndrome have severe intellectual disability and delayed development, speak very little and often laugh and smile for no apparent reason. Angelman syndrome is usually diagnosed using a genetic test called DNA microarray testing. Angelman syndrome can’t be cured, but there is a range of therapies that can improve the quality of life of those affected. What is Angelman syndrome? Angelman syndrome is a genetic condition. It occurs if a gene called UBE3A is missing or faulty. When this