Anaphylaxis

Overview Anaphylaxis is a serious systemic hypersensitivity (allergic) reaction that is rapid in onset and may cause death. Anaphylaxis can be a life-threatening condition that is broadly defined as a severe, generalised or systemic hypersensitivity reaction that is characterised by airway and/or breathing and/or circulation problems that is usually associated with skin and mucosal changes (i.e. urticaria and angio-oedema). Features of anaphylaxis are usually sudden with rapid progression so urgent assessment and management is vital. Anaphylaxis is the most severe form of an allergic reaction that forms part of a spectrum. Allergic reactions are characterised by skin changes (e.g. urticaria)