Acromegaly
Overview Acromegaly is a condition caused by an excess of growth hormone (GH) most commonly related to a pituitary adenoma. It tends to present with macrognathia, frontal bossing and enlargement of hands and feet. Presentation may also be related to the aetiology – e.g. mass effect of a pituitary adenoma resulting in visual field defects and headache. It is associated with a number of systemic conditions (e.g. cardiovascular disease, diabetes). The condition is thought to be rare though the true prevalence is hard to establish. Recent studies estimate a prevalence of up to 1 in 1000 individuals in patients who
