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1. According to Pasteur statements which one of the following is true
a. Living organisms discriminate between
stereoisomers
b. Fermentation is a aerobic process
c. Living organisms doesn’t discriminate between stereoisomers
d. Both a and b
2. “I found floating therin earthly particles, some green streaks, spirally wound serpent-wise, and orderly arranged, the whole circumstance of each of these streaks was abut the thickness of a hair on one’s head”…. These words are of
a. Leeuwenhoek
b. A. Jenner
c. Pasteur
d. Koch
3. The principle light- trapping pigment molecule in plants, Algae, and cyanobacteria is
a. Chlorophyll a
b. Chlorophyll b
c. Porphyrin
d. Rhodapsin
4. During Bio Geo chemical cycle some amount of elemental carbon was utilized by the microorganisms. The phenomenon is called as
a. Dissimilation
b. Immobilization
c. Decomposition
d. Neutralization
5. Who demonstrated that open tubes of broth remained free of bacteria when air was free of dust.
a. Abbc Spallanzani
b. John Tyndall
c. Francisco Redi
d. Pasteur
6. Reverse isolation would be appropriate for
a. a patient with tuberculosis
b. a patient who has had minor surgery
c. a patient with glaucoma
d. a patient with leukemia
7. The symptome “ general feeling of illness and discomfort “ is called
a. Cystitis
b. Malaise
c. Anaphylactic shock
d. Arthritis
8. On soybean which of the following forms symbiotism
a. Azatobactor paspali
b. Rhizobium
c. Nostoc
d. Bradyrhizobium
9. Who provide the evidence that bacteriophage nucleic acid but not protein enters the host cell during infection
a. Alfred D.Hershey & Leonard Tatum in 1951.
b. Alfred D.Hershey & Zindar Lederberg in 1951.
c. Alfred D.Hershey & Martha Chase in 1952.
d. Alfred D.Hershey & Macleod in 1952.
10. Spirulina belongs to
a. Xanthophyceae
b. Cyanophyceae
c. Rhodophyceae
d. Pheophyceae
11. The first antibody to contact invading microorganisms was
a. IgG
b. IgM
c. IgA
d. IgD
12. The light emitted by luminescent bacteria is mediated by the enzyme
a. Coenzyme Q
b. Luciferase
c. Lactose dehydrogenase
d. Carboxylase reductase
13. Pick out the vector using in human Genome project
a. Phagemid vector
b. Yeast artificial chromosomes
c. Cosmid vectors
d. Yeast episomal plasmids
14. Salt and sugar preserve foods because they
a. Make them acid
b. Produce a hypotonic environment
c. Deplete nutrients
d. Produce a hypertonic environment
15. In a fluorescent microscope the objective lens is made of
a. Glass
b. Quartz
c. Polythene
d. None of these
16. Fixation of atmospheric nitrogen is by means of
a. Biological process
b. Lightining
c. Ultraviolet light
d. All of the above
17. Which one of the following fungi is the most serious threat in a bone marrow transplant unit?
a. Candida albicans
b. Aspergillus
c. Blastomyces
d. Cryptococus
18. Direct microscopic count can be done with the aid of
a. Neuberg chamber
b. Anaerobic chamber
c. Mineral oil
d. Olive oil
19. The image obtained in a compound microscope is
a. Real
b. Virtual
c. Real inverted
d. Virtual inverted
20. Enzymes responsible for alcohol ic fermentation
a. Ketolase
b. Zymase
c. Peroxidase
d. Oxidase
21. Which type of spores are produced sexually?
a. Conidia
b. Sporangiospores
c. Ascospores
d. None of these
22. Bacterial transformation was discovered by
a. Ederberg and Tatum
b. Beadle and Tatum
c. Griffith
d. None of these
23. Father of microbiology is
a. Louis Pasteur
b. Lister
c. A.V. Leeuwenhock
d. Robert Koch
24. The antiseptic method was first demonstrated by
a. Lwanowski
b. Lord Lister
c. Edward Jenner
d. Beijerinck
25. Small pox vaccine was first discovered by
a. Robert Koch
b. Louis Pasteur
c. Lister
d. Edward Jenner
26. The term mutation was coined by
a. Pasteur
b. Darwin
c. Hugo devries
d. Lamark
27. Compound microscope was discovered by
a. Antony von
b. Pasteur
c. Johnsen & Hans
d. None of these
28. Father of Medical Microbiology is
a. Pasteur
b. Jenner
c. Koch
d. A.L.Hock
29. Disease that affects many people at different countries is termed as
a. Sporadic
b. Pandemic
c. Epidemic
d. Endemic
30. Prophylaxis of cholera is
a. Protected water supply
b. Environmental sanitation
c. Immunization with killed vaccines
d. All of these
31. In electron microscope, what material is used as an objective lense?
a. Magnetic coils
b. Superfine glass
c. Aluminium foils
d. Electrons
32. The main feature of prokaryotic organism is
a. Absence of locomotion
b. Absence of nuclear envelope
c. Absence of nuclear material
d. Absence of protein synthesis
33. The stalked particles on the cristae of mitochondria are called
a. Glyoxysomes
b. Peroxisomes
c. Oxysomes
d. Spherosomes
34. Antiseptic methods were first introduced by
a. Lord Lister
b. Iwanowski
c. Beijernick
d. Edward Jenner
35. Kuru disease in Humans is caused by
a. Bacteria
b. Viroides
c. Prions
d. Mycoplasma
36. A mutation that produces termination codon is
a. Mis-sense mutation
b. Neutral mutation
c. Non-sense mutation
d. Reverse mutation
37. During conjunction the genetic material will be transferred through
a. Cell wall
b. Medium
c. Pili
d. Capsule
38. Antiseptic surgery was discovered by
a. Joseph Lister
b. Ernest Abbe
c. Pasteur
d. Beijerink
39. Tuberculosis is a
a. Water borne disease
b. Air borne disease
c. Food borne disease
d. Atthropod borne disease
40. Phagocytic phenomenon was discovered by
a. Louis Pasteur
b. Alexander Fleming
c. Metchnikof
d. Robert Koch
41. Meosomes are also known as
a. Mitochondria
b. Endoplasmic reticulum
c. Plasmids
d. Chondroids
42. Hybridoma technique was first discovered by.
a. Kohler and Milstein
b. Robert Koch
c. ‘D’ Herelle
d. Land Steiner
43. The m in imum number of bacter ia required to produce clinical evidence of death in a susceptible animal under standard condition is called
a. LD50
b. ID
c. MLD
d. All of these
44. In Electron Microscope source of electrons is from
a. Mercury lamp
b. Tungsten metal
c. both a and b
d. None of these
45. Griffith (1928) reported the phenomenon of transformation first in
a. H. influenzae
b. Bacillus species
c. Pneumococci
d. E.coli
46. The resolution power of the compound microscope is
a. 0.2 micron
b. 0.2 millimeter
c. 0.2 Angstrom units
d. 0.2 centimeter
47. The capacity of a given strain of microbial species to produce disease is known as
a. Pathogen
b. Virulence
c. Infection
d. None of these
48. Monoclonal antibodies are associated with the name of
a. Burnet
b. Medwar
c. Milstein kohler
d. Owen
49. Lederberg and Tatum (1946) described the phenomena of
a. Conjunction
b. Transformation
c. Mutation
d. Plasmids
50. Hanging drop method for motility study was first introduced by
a. Robert Koch
b. Louis Pasteur
c. Jenner
d. Leeuwenhock
51. Electron microscope gives magnification upto
a. 100 X
b. 2000 X
c. 50,000 X
d. 2,00,000 X
52. Term vaccine was coined by
a. Robert Koch
b. Pasteur
c. Needham
d. None of these
53. The inventor of Microscope is
a. Galileo
b. Antony von
c. Pasteur
d. Koch
54. First Pasteur conducted fermentation experiments in
a. Milk
b. Food material
c. Fruit juices
d. Both a and c
55. Modern concepts of chemotherapy was proposed by
a. Paul Ehrlich
b. Joseph Lister
c. Elie Metchnikoff
d. None of these
56. The role of phagocytosis was discovered by
a. Paul Ehrlich
b. Joseph lister
c. Elie Metchikoff
d. Pasteur
57. L – forms are discovered by
a. Klein Berger
b. Louis Pasteur
c. Robert Koch
d. Antony von Leeuwenhocka
58. The causative organism of rocky mountain spotted fever was first described by
a. Howard Ricketts
b. da Rocha-lima
c. Both a and b
d. Robert Koch
59. The term bacteriophage was coined by
a. De’Herelle
b. F.W. Twort
c. Beijernick
d. Jwanosky
60. Viral infection of bacteria was discovered by
a. De’Herelle
b. F.W. Twort
c. Beijernick
d. Jwanoksy
61. Eye cannot resolve any image less than
a. 1ìm
b. 2ìm
c. 7ìm
d. 5ìm
62. Compound Microscope was discovered by
a. A.V. Lewenhoek
b. Pasteur
c. Janssen and Hans
d. None of these
63. Electron Microscope was discovered by
a. Prof. Fritz
b. Janssen and Hans
c. Knoll and Ruska
d. None of these
64. Magnification range of light microscope is
a. 1000x – 5000x
b. 1000x – 2000x
c. 500x – 1000x
d. None of these
65. Condensation of light in light Microscope is by
a. Objective
b. Condensor
c. Ocular
d. All of these
66. Light gathering capacity of Microscope is called
a. Numerical aperture
b. Angular aperture
c. Both a and b
d. None of these
67. If 10x and 40x objectives are used (air is the medium), the numerical aperture is
a. 1.5
b. 2.0
c. 1.0
d. 1.8
68. The ability of Microscope to distinguish two objects into two separate objects, is called.
a. Resolving power
b. Wave length
c. N.A.
d. None of these
69. Limit of resolution of compound microscope is
a. 0.018 Ao
b. 0.1 mm
c. 5 ìm
d. 1 mm
70. Source of light in fluorescence microscopy is from
a. Mercury lamp
b. Sunlight
c. Both a and b
d. None of these
71. Who perfected a magnetic lens in 1927
a. Gabor
b. Broglie
c. Busch
d. None of these
72. The magnefication power of electron microscope developed by Knell and Ruska is
a. 10,000x
b. 12,000x
c. 15,000x
d. 20,000x
73. In electron microscope source of electrons is from
a. Mercury lamp
b. Tungsten metal
c. Both a and b
d. None of these
74. The e lectron passed out from the specimen are called
a. Primary electrons
b. Secondary electrons
c. Tertiary electrons
d. None of these
75. Mycorrhiza was first observed by
a. Funk
b. Frank
c. Fisher
d. Crick
76. The transfer of genetic material during transformation is proved basing on Griffith’s experiment by
a. Avery Macleod & Mc.Carthy
b. Lederberg & Taulum
c. Zinder & Lederberg
d. Watson & Crick
77. Phagocytic theory was proposed by
a. Louis Pasteur
b. Elie Metchnikoff
c. Behring
d. Widal
78. Anaphylaxia was first observed by
a. Parter & Richet
b. Coombs
c. Gell
d. None of these
79. Primary mediators in anaphylaxis
a. Histamine
b. Seratonin
c. Heparin
d. All of these
80. Arthus reaction was discovered by
a. Marrice Arthus
b. Von Perquit
c. Richet
d. Porter
81. Serum sickness reaction was discovered by
a. Marrice Arthus
b. Von perquit
c. Richet
d. Porter
82. Hybridoma technique was developed by
a. Kochler & Milston
b. Niel’s Jerne
c. Both a and b
d. None of these
83. Disease that effects many people at different countries is termed as
a. Sporadic
b. Pandemic
c. Epidemic
d. Endemic
84. If the vectors transmit the infection mechanically they are called
a. Biological vectors
b. Mechanical vectors
c. Biological reservoir
d. Both a and c
85. If a person can be infected by direct contact with infected tissue of another person, it is termed as
a. Indirect contact transmission
b. Attachment
c. Direct contact transmission
d. None of these
86. Reduction of virulence is known as
a. Exaltation
b. Attenuation
c. Both a and b
d. None of these
87. Enhancement of virulence is known as
a. Exaltation
b. Attenuation
c. Both a and b
d. None of these
88. The virulence of a pathogen is usually measured by
a. LD
b. MLD
c. ID
d. All of the above
89. The lethal dose required to kill 50% of the lab animals tested under standard called
a. ID
b. LD50
c. ID50
d. MLD
90. The most important virulence factors are
a. Adhesions
b. Invasiveness
c. Toxigenicity
d. Enzymes
e. All of the above
91. The ability of a pathogen to spread in ths host tissues after establishing the infection is known as
a. Adhesion
b. Invasiveness
c. Toxigenicity
d. None of these
92. Which is the following enzyme acts as a spreading factor?
a. Hyaluronidase
b. Coagulase
c. Catalase
d. DNase
93. Vibrio Cholerae was discovered by
a. Koch
b. Metchnikoff
c. John Snow
d. Virchow
94. E.coli was first isolated by
a. Louis Pasteur
b. Escherich
c. Shiga
d. Robert Koch
95. Mycobacterium tuberculosis was first discovered by
a. Robert Koch
b. Edward Jenner
c. Louis Pasteur
d. None of these
96. Mycobacterium lepree was discovered by
a. Robert Koch
b. Hansen
c. Edward Jenner
d. Louis Pasteur
97. Streptococcus pneumoniae was isolated by
a. Robert Koch
b. Edward Jenner
c. Antony von Leewenhock
d. Louis Pasteur
98. B.anthracis was isolated by
a. Louis Pasteur
b. Robert Koch
c. Antonyvon Leewenhok
d. None of these
99. Staphylococcus aureus was isolated by
a. Rosenbach
b. Louis Pasteur
c. Passet
d. Sir Alexander Ogston
100. Pseudomonas aeruginosa was first named
a. Schroeter and Gessard
b. Robert Koch
c. Louis Pasteur
d. Edward Jenner
101. T. pallidum was discovered by
a. Robert Koch
b. Schaudinn and Hoffman
c. Louis Pasteur
d. Edward Jenner
102. Neisseria gonorrhoeae was first described by
a. Neisser in 1879
b. Pasteur in 1878
c. Robert Koch
d. None of these
103. Rh factor of the blood was discovered by scientist
a. Louis Pasteur
b. Landsteiner and Weiner
c. Janskey
d. Moss
e. None of these
104. Trepanema pallidum was discovered by
a. Schaudinn and Hoffman
b. Louis Pasteur
c. Burgey
d. Laennec
e. None of these
105. Fluroscent substance used in fluorescent microscopy are
a. Quinine sulphate
b. Auramine
c. All of these
d. None of these
