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Gastro-Intestinal System

Which drug blocks the proton pump?
A. omeprazole
B. almagel
C. famotidine
D. atropine
E. misoprostol

Correct answer is :
Omeprazole

Which of the following drugs maximally inhibits the secretion of hydrochloric acid:
A. famotidine
B. ranitidine
C. misoprostol
D. omeprazole
E. atropine

Correct answer is :
Omeprazole

Which of the following drugs promotes eradication of H.pylori:
A. azithromycin
B. famotidine
C. clarithromycin
D. lincomycin
E. gentamicin

Correct answer is :
Clarithromycin

Which anti-ulcer agents can cause hypophosphatemia:
A. aluminum-containing antacids
B. bismuth-containing medications
C. Proton pump blockers
D. H2-histamine blockers
E. synthetic prostaglandins

Correct answer is :
Aluminum-containing antacids

Which receptors are affected by famotidine:
A. M1-cholinoreceptors
B. M2-cholinoreceptors
C. H1-histamine receptors
D. H2-histamine receptors
E. N-cholinoreceptors

Correct answer is :
H2-histamine receptor

Which drug neutralizes hydrochloric acid:
A. ranitidine
B. maalox
C. misoprostol
D. omeprazole
E. pantoprazole

Correct answer is :
Maalox

Which drug combination potentiates the bactericidal effect on H.pylori:
A. de-nol + famotidine
B. de-nol + amoxicillin
C. almagel + amoxicillin
D. fosfogel + famotidine
E. maalox + clarithromycin

Correct answer is :
De-nol + Amoxicillin

State what is not a side effect of absorbable antacids:
A. metabolic alkalosis
B. hyperNa+emia
C. withdrawal syndrome
D. hypophosphatemia
E. hypertension

Correct answer is :
Hypophosphatemia

Which drug is characterized by withdrawal syndrome:
A. de-nol
B. famotidine
C. Venter
D. almagel
E. omeprazole

Correct answer is :
Famotidine

Which pharmacodynamic effect is not characteristic of misoprostol:
A. antisecretory
B. antispasmodic
C. regenerative
D. stimulation of mucus production
E. improvement of blood circulation in gastric mucosa

Correct answer is :
Antispasmodic is not a pharmacodynamic effect of misoprostol

Which drug inhibits the ulcerogenic effect of NSAIDs:
A. almagel
B. atropine
C. famotidine
D. sucralfate
E. misoprostol

Correct answer is :
Misoprostol

The following statement about antacids is incorrect:
A. magnesium salts cause diarrhea
B. all antacids may cause edema in patients with heart disease
C. Al-hydroxide is the antacid of choice in patients with CKD
D. Alkalosis occurs more often with sodium hydrocarbonate than with other antacids
E. Aluminum salts cause constipation

Correct answer is :
All antacids may cause edema in patients with heart diseases

Choose the correct omeprazole regimen for the period of H. Pylori eradication:
A. 20 mg 3 times/day
B. 20 mg 2 times/day
C. 20 mg daily
D. 40 mg daily
E. 60 mg daily

Correct answer is :
20mg 2 times/day

The maximum number of side effects among H2 – blockers causes:
A. cimetidine
B. roxatidine
C. ranitidine
D. famotidine
E. nizatidine

Correct answer is :
cimetidine

Which prokinetic does not penetrate the CNS and does not cause adverse effects on the nervous system:
A. metoclopramide
B. cimetidine
C. domperidone
D. all of the above
E. none of the above

Correct answer is :
domperidone

Cytoprotectors that form a protective film include:
A. misoprostol
B. de-nol
C. famotidine
D. omeprazole
E. pantoprazole

Correct answer is :
de-nol

Non-absorbable antacids do not include:
A. gelusil
B. maalox
C. almagel
D. fosfalugel
E. Rennie

Correct answer is :
Rennie

Products that suppress Helicobacter infection include all except:
A. tetracycline
B. metronidazole
C. amoxicillin
D. gentamicin
E. clarithromycin

Correct answer is :
Gentamicin

Select the indication for prescribing antacids in peptic ulcer disease:
A. are the main drug in eradication regimens
B. used for relief of pain and heartburn
C. used for recovery after conducted course of eradication
D. used as a bactericidal agent
E. all indications listed above

Correct answer is :
used for relief of pain and heartburn

A three-component regimen for eradication of H. Pylori includes:
A. famotidine + omoprazole + amoxicillin
B. omeprazole + amoxicillin + clarithromycin
C. famotidine+ amoxicillin+ clarithromycin
D. omeprazole+ de nol+famotidine
E. omeprazole + amoxicillin + lincomycin

Correct answer is :
omeprazole + amoxicillin + clarithromycin

For eradication of H. .pylori use:
A. metronidazole
B. clarithromycin
C. amoxicillin
D. tetracycline
E. all of the above

Correct answer is :
All listed drugs are used for H. Pylori eradication

State one important advantage of omeprazole over H2-histamine receptor blockers:
A. the cheapness of the drug
B. no withdrawal syndrome
C. suppresses secretion of hydrochloric acid
D. has cytoprotective effect
E. has bactericidal action against H. pylori