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Blood and hemostasis

State a drug that is a direct anticoagulant:
A. alteplase
B. warfarin
C. clopidogrel
D. fractiparin
E. aspirin

Correct answer is :
Fractiparin

Specify the drug belonging to the group of antiaggregants:
A. Fraxiparin
B. acetylsalicylic acid
C. urokinase
D. hirudin
E. warfarin

Correct answer is :
Acetylsalicylic acid

Identify the drug belonging to the group of thrombolytics:
A. acetylsalicylic acid
B. tenecteplase
C. warfarin
D. heparin
E. fractiparin

Correct answer is :
tenecteplase

What is the mechanism of antiplatelet action of acetylsalicylic acid:
A. reversible inhibition of cyclooxygenase
B. inhibition of thromboxanthase
C. blockade of glycoprotein IIb/IIIa complexes
D. irreversible inhibition of cyclooxygenase activity
E. fibrin dissolution

Correct answer is :
Irreversible inhibition of cycle-oxygenase activity

State the index that should be monitored during heparin therapy:
A. prothrombin time
B. activated partial thromboplastin time
C. international normalized ratio
D. bleeding time
E. all of them

Correct answer is :
aPTT – activated Partial Thromboplastin Time

State the mechanism of anticoagulant action of heparin:
A. inhibition of thrombin independent of antithrombin III
B. inhibition of thrombin activity in presence of antithrombin III
C. disturbance of formation of active form of vitamin K in the liver
D. dissolution of fibrin
E. COX blockade

Correct answer is :
Inhibition of thrombin activity in presence of antithrombin III

Which class of drugs fraxiparin belongs to:
A. thrombolytics
B. antiaggregants
C. vitamin K antagonists
D. low-molecular-weight heparins
E. statins

Correct answer is :
Low molecular weight heparins

Choose a fibrinolytic for bolus administration:
A. alteplase
B. streptokinase
C. dialysis
D. purolase
E. actylase

Correct answer is :
dialysis

To dissolve the fibrin clot, use:
A. heparin
B. aspirin
C. clopidogrel
D. alteplase
E. clexane

Correct answer is :
Alteplase

Which index should be monitored during warfarin treatment:
A. ACTV
B. bleeding time
C. INR
D. clotting time
E. leucocyte count

Correct answer is :
INR – International Normalization Ratio

State the mechanism of action of clopidogrel:
A. COX blockade
B. IIb receptor blockade\IIIa
C. blockade of ADP receptors
D. blockade of clotting factor synthesis in liver
E. increase in plasmin synthesis