Nasal polyp
This is a benign, inflammatory proliferation of the lining of the nose, which usually occurs after recurrent colds (infective sinusitis).
Associations
Eosinophilic granulomatosis with polyangiitis
Conditions causing poor cilia motility, e.g., cystic fibrosis and primary ciliary dyskinesia (previously known as Kartagener’s syndrome)
Samter’s triad – nasal polyps and asthma in conjunction with aspirin sensitivity
Symptoms
Nasal congestion
Rhinorrhoea
Changes to taste (ageusia) and smell (anosmia)
Management
Steroid spray to reduce size of polyp
If remains persistent, refer to ENT for examination and removal
Nasopharyngeal Carcinoma
This is a malignant squamous cell tumour of the nasopharynx.
It is rare in most parts of the world, except in southern China, and is associated with the Epstein-Barr virus (EBV).
Symptoms
Nasal obstruction, discharge and epistaxis
Cervical lymphadenopathy
Spread into the ears leads to otalgia and unilateral serous otitis media
Visual changes (secondary to spread to the brain which can compress CN V and VI particularly)
Key tests
Nasal endoscopy with biopsy for histological analysis.
CT/MRI for staging
Management
Radiotherapy and chemotherapy
Vocal Cord Nodule
This refers to a nodule growing on the true vocal cords, which causes hoarseness of voice and a reduced vocal range.
It is usually due to excessive use of the vocal cords (e.g., singing).
Key tests
Laryngeal endoscopy is the diagnostic test
Management
1st line is resting the voice, if unresolving may require surgery
Laryngeal Carcinoma
This is a squamous cell cancer of the cells which form the larynx.
It is associated with smoking and chronic alcohol use.
Risk Factors
Smoking
Chronic alcohol use
Symptoms
Hoarse voice
Sore throat
Neck lump
Key tests
For laryngeal masses, larynx is observed by indirect laryngoscopy
A tissue biopsy will be undertaken to obtain a sample of tissue
Management
Surgery with adjuvant chemo/radiotherapy
NICE Referral Guidelines
Epistaxis
This refers to nosebleeds which can be split into anterior and posterior bleeds.
Anterior bleed
This occurs due to trauma to the blood vessels that form Kiesselbach’s plexus.
Bleeding occurs out of the front of the nose and is visible.
Posterior bleed
These are more profuse, originating from Woodruff’s plexus.
They occur more frequently in older patients, leading to higher risk of aspiration.
Management
If hemodynamically stable, ask the patient to sit forward with their mouth open and pinch soft area of nose for 15 minutes
Then use topical antiseptic (e.g., naseptin) to reduce crusting and risk of vestibulitis
If bleeding does not stop after 15 minutes, use cautery if source of bleed is visible
Otherwise, use nasal packing and admit to hospital for observation and ENT review
If patient is hemodynamically unstable, will need fluid resuscitation +/- surgery