Hydromorphone

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Key facts

  • Hydromorphone is a strong opioid-based pain medicine that can only be prescribed by your doctor.
  • Hydromorphone is prescribed for the short-term relief of severe pain, where other pain-relief medicines have not been effective or cannot be used.
  • Hydromorphone is not the same as morphine — it is much more potent (stronger), so take care not to confuse the two.
  • Always take hydromorphone exactly as prescribed by your doctor.
  • Don’t stop taking hydromorphone suddenly, as you may experience withdrawal symptoms.

What is hydromorphone?

Hydromorphone is a strong opioid pain medicine available on prescription from your doctor.

 

What is hydromorphone used for?

Hydromorphone is used for the short-term relief of severe pain, where other pain medicines have not been effective or cannot be used. It is more potent (stronger) than morphine and should only be used with specialist medical care.

Hydromorphone should also be used only when other forms of pain relief have not been successful in managing pain.

How does hydromorphone work?

Hydromorphone works directly on opioid receptors in the central nervous system. It reduces feelings of pain by interrupting the way nerves signal pain between the brain and the body.

What forms of hydromorphone are available?

Hydromorphone comes in different dosages and forms including:

  • tablets
  • oral liquid
  • injections

Hydromorphone should only be used in limited circumstances under specialist medical care.

How do I take hydromorphone?

It is important to follow the directions given to you by your doctor or pharmacist. Your doctor will write the recommended dosage on your prescription.

If you have been taking hydromorphone for more than a short while, it is also important not to suddenly stop taking this medicine. You should gradually reduce the amount you are taking – under the supervision of your doctor. This will help to reduce your risk of having withdrawal symptoms.

What are the possible side effects of taking hydromorphone?

All opioids, including hydromorphone, can have side effects that include life-threatening breathing problems. The risk of these is higher:

  • when first taking hydromorphone
  • after a dosage increase
  • if you are older
  • if you have an existing lung problem

The side effects of hydromorphone are similar to those of other opioids, and include:

  • constipation
  • headache or dizziness
  • fatigue or drowsiness (especially right after a dose)
  • loss of appetite, nausea and vomiting

Hydromorphone affects everyone differently. If your pain is not well managed while taking hydromorphone, or if you notice your medicines are making you feel unwell, speak with your pharmacist or doctor.

Always take medicines exactly as prescribed by your doctor.

What are the risks associated with hydromorphone?

Opioids are strong pain-relief medicines and can cause life-threatening breathing problems. Hydromorphone may make you feel drowsy, and make it difficult for you to drive or operate heavy machinery. If you have recently started taking an opioid medicine or changed dosage, you may be at a higher risk of having an accident.

If you have kidney problems or your kidney function is impaired, your doctor will need to adjust your dosage of hydromorphone.

There are other factors that may limit your use of hydromorphone — for example, if you drink alcohol or take other medicines that can cause drowsiness.

Your doctor is the best person to advise you on whether hydromorphone is the right medicine for you, how much you need and how long to take it for.

Are there any alternatives to hydromorphone?

Remember that everyone’s pain is unique and different pain-relief medicines will work in different circumstances. Some people’s pain will respond well to non-opioid medicines. You may also find that one opioid helps you manage your pain better and with fewer side effects than another.

Hydromorphone is not the same as morphine — it is much stronger, which means it can be much more dangerous if taken inappropriately. Take care not to confuse hydromorphone with morphine.

Your doctor may prescribe hydromorphone if other pain medicines, such as morphine, are not effective or if you have side effects.

Always check with your doctor or pharmacist before making any change to the dosage or type of medicine you take.

If you have chronic (long-term) pain, your doctor might suggest lifestyle changes to help manage the discomfort. This may include:

  • improving your physical fitness
  • activity pacing
  • social activities
  • relaxation techniques
  • overall health management

Find out more about options for managing chronic pain.

When should I see my doctor?

If your pain is not well controlled on hydromorphone, or you have any unexpected side effects, see your doctor.

How do I dispose of medicines safely?

It’s important you dispose of unwanted opioid medicines safely. Unused medicines can be returned to any pharmacy. Don’t keep unused hydromorphone ‘just in case’, as this can lead to dangerous or inappropriate use.

Keep hydromorphone out of reach of children and pets. Never throw medicines into a garbage bin or flush them down the toilet, as this is dangerous to others and harmful to the environment.

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