Day: October 12, 2022

Haemolytic anaemia

Haemolysis refers to the destruction of red blood cells (RBCs), which is broadly defined as a reduction in the life span below 100 days (normal 110-120 days). Haemolytic anaemia is defined as anaemia secondary to reduced survival of RBCs. They have a varied aetiology, as is the clinical presentation; together they represent approximately 5% of all anaemias. Regardless of the underlying cause, if erythropoiesis within the bone marrow cannot keep pace with the destruction of RBCs anaemia will ensue. Mild haemolysis may be completely asymptomatic whereas severe, acute haemolysis will lead to cardiopulmonary decompensation. Classification Haemolytic anaemia can be classified as inherited or aquired. Inherited