Cardiac Marker Changes Over Time

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Cardiac Marker Changes

Cardiac markers are used in the diagnosis and risk stratification of patients with chest pain and suspected acute coronary syndrome (ACS).^�The cardiac troponins, in particular, have become the cardiac markers of choice for patients with ACS. Cardiac troponin is central to the definition of acute myocardial infarction (MI)^�in the consensus guidelines from the European Society of Cardiology (ESC) and the American College of Cardiology (ACC).

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Table 1. Cardiac Marker Changes Over Time

Marker	Onset (hours)	Peak (hours)	Duration
Troponin I	3-12	10-24	3-10 days
Troponin T	3-12	12-48	5-14 days
Creatine kinase-MB (CK-MB)	4-6	24	2-3 days
Myoglobin	2-4	6-12	24-36 hours