Advanced Cardiac Life Support (ACLS): Adult Cardiac Arrest�

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Advanced Cardiac Life Support (ACLS): Adult Cardiac Arrest

ACLS: Adult Arrest

1. The initial evaluation is as follows:

  • Activate emergency response system.
  • Initiate adult basic life support (BLS) algorithm.

2. The initial intervention is as follows:

  • Start high-quality cardiopulmonary resuscitation (CPR).
  • Administer oxygen if hypoxemic.
  • Attach monitor/defibrillator.
  • Monitor blood pressure and oximetry; do not delay defibrillation.

3. Check rhythm, as follows:

  • Shockable rhythm = Ventricular fibrillation or pulseless ventricular tachycardia (VF/VT)
  • Nonshockable rhythm = Asystole/pulseless electrical activity (PEA)

Shockable Rhythm

1. Initial treatment of VT/VF is as follows:

  • Defibrillate immediately.
  • Continue CPR for 2 minutes.
  • Obtain intravenous (IV)/intraosseous (IO) acess; IO access if IV not possible.
  • Consider advanced airway, end-tidal carbon dioxide tension (PETCO 2).

2. Administer vasopressor (epinephrine q3-5min)

3. Check pulse and rhythm every 2 minutes, as follows:

  • If nonshockable, see Nonshockable Rhythm (below).
  • If shockable, see Shockable Rhythm (above) and administer amiodarone after second defibrillation attempt.
  • Rotate chest compressors.
  • Identify and treat reversible causes.

4. If return of spontaneous circulation (ROSC),see ACLS: Post-Cardiac Arrest Care.

Nonshockable Rhythm

1. Initial treatment of asystole/PEA is as follows:

  • Continue CPR for 2 minutes.
  • Obtain intravenous (IV)/intraosseous (IO) access.
  • Consider advanced airway, end-tidal carbon dioxide tension (PETCO 2).

2. Administer vasopressor (epinephrine q3-5min).

3. Check pulse and rhythm every 2 minutes, as follows:

  • If nonshockable, see Nonshockable Rhythm (above).
  • If shockable, see Shockable Rhythm (above).
  • Rotate chest compressors.
  • Identify and treat reversible causes.

4. If return of spontaneous circulation (ROSC), see ACLS: Post-Cardiac Arrest Care

CPR Quality

CPR should proceed as follows:

  • Push hard and fast, at least 2 inches (5 cm) and 100-120 compressions per minute.
  • Allow complete chest recoil.
  • Minimize interruptions in compressions.
  • Avoid excessive ventilation.
  • Rotate compressor every 2 minutes or if fatigued.
  • Compression-to-ventilation ratio is 30:2.
  • Continuous compressions if advanced airway present
  • If PETCO 2 is low or decreasing, attempt to improve CPR quality

Shock Energy

Shock energy should be as follows:

  • Biphasic: Manufacturer recommendation (eg, 120-200 J initial); if unknown, use maximum available.
  • Monophasic: 360 J

Drug Therapy

Drug therapy consists of the following:

  • Epinephrine 1 mg IV/IO q3-5min
  • Amiodarone 300 mg IV/IO initial bolus dose, amiodarone 150 mg IV/IO second dose OR
  • Lidocaine 1st dose 1-1.5mgkg, 2nd dose 0.5-0.75mg/kg
  • Flush medications with 20 mL fluid after and elevate extremity for 10-20 seconds.
  • Combining medications is not recommended and may cause harm.
  • Routine use of sodium bicarbonate is not recommended and may cause harm (eg, if inadequate ventilation)
  • Routine use of magnesium for VF/VT is not recommended in adult patients.

Advanced Airway

Advanced airway should be established as follows:

  • Endotracheal tube (ETT) or supraglottic airway (SGA)
  • Waveform capnography to confirm and monitor ET tube placement
  • Ventilation every 6 seconds asynchronous with compressions
  • Stop CPR for no longer than 10 seconds for the placement of an advanced airway.

Return of Spontaneous Circulation

Signs of ROSC include the following:

  • Pulse and blood pressure present
  • Abrupt sustained increase in PETCO 2 (typically >40 mm Hg)
  • Spontaneous arterial pressure waves with intra-arterial monitoring

Reversible Causes (H’s and T’s)

Reversible causes include the following:

  • H’s: hypovolemia, hypoxia, H+ (acidosis), hypokalemia, hyperkalemia, hypothermia
  • T’s: toxins, tamponade (cardiac), tension pneumothorax, thrombosis (pulmonary, coronary)

Updates from the 2015 guidelines:

The following are updates from the 2015 guidelines:

  • Continuous measurement of arterial blood pressure and end-tidal carbon dioxide (ETCO2) can improve CPR quality during ALS resuscitation.
  • Routine use of double sequential defibrillation is not recommended.
  • Intravenous (IV) access is now the preferred route of administration during ACLS resuscitation. Intraosseous (IO)access is acceptable in the case that IV is not possible.
  • Care after ROSC including consideration of percutaneous coronary intervention, temperature control and multimodal neuroprognostication.
  • Emphasis on post cardiac arrest care including detailed assessment of physical, cognitive, and psychosocial needs.
  • Importance of debriefing individuals involved in the cardiac arrest team.

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Dr. Ahmed Hafez