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Advanced Cardiac Life Support (ACLS): Adult Cardiac Arrest
ACLS: Adult Arrest
1. The initial evaluation is as follows�:
- Activate emergency response system.
- Initiate adult basic life support (BLS) algorithm.
2. The initial intervention is as follows:
- Start high-quality cardiopulmonary resuscitation (CPR).
- Administer oxygen if hypoxemic.
- Attach monitor/defibrillator.
- Monitor blood pressure and oximetry; do not delay defibrillation.
3. Check rhythm, as follows:
- Shockable rhythm = Ventricular fibrillation or pulseless ventricular tachycardia (VF/VT)
- Nonshockable rhythm = Asystole/pulseless electrical activity (PEA)
Shockable Rhythm
1. Initial treatment of VT/VF is as follows:
- Defibrillate immediately.
- Continue CPR for 2 minutes.
- Obtain intravenous (IV)/intraosseous (IO) acess; IO access if IV not possible.
- Consider advanced airway, end-tidal carbon dioxide tension (PETCO 2).
2. Administer vasopressor (epinephrine q3-5min)
3. Check pulse and rhythm every 2 minutes, as follows:
- If nonshockable, see Nonshockable Rhythm (below).
- If shockable, see Shockable Rhythm (above) and administer amiodarone after second defibrillation attempt.
- Rotate chest compressors.
- Identify and treat reversible causes.
4. If return of spontaneous circulation (ROSC),see ACLS: Post-Cardiac Arrest Care.
Nonshockable Rhythm
1. Initial treatment of asystole/PEA is as follows:
- Continue CPR for 2 minutes.
- Obtain intravenous (IV)/intraosseous (IO) access.
- Consider advanced airway, end-tidal carbon dioxide tension (PETCO 2).
2. Administer vasopressor (epinephrine q3-5min).
3. Check pulse and rhythm every 2 minutes, as follows:
- If nonshockable, see Nonshockable Rhythm (above).
- If shockable, see Shockable Rhythm (above).
- Rotate chest compressors.
- Identify and treat reversible causes.
4. If return of spontaneous circulation (ROSC), see ACLS: Post-Cardiac Arrest Care
CPR Quality
CPR should proceed as follows�:
- Push hard and fast, at least 2 inches (5 cm) and 100-120 compressions per minute.
- Allow complete chest recoil.
- Minimize interruptions in compressions.
- Avoid excessive ventilation.
- Rotate compressor every 2 minutes or if fatigued.
- Compression-to-ventilation ratio is 30:2.
- Continuous compressions if advanced airway present
- If PETCO 2 is low or decreasing, attempt to improve CPR quality
![](https://medicine-21.com/physicians/wp-content/uploads/2024/05/sdfsd-1-1.png)
Shock Energy
Shock energy should be as follows:
- Biphasic: Manufacturer recommendation (eg, 120-200 J initial); if unknown, use maximum available.
- Monophasic: 360 J
Drug Therapy
Drug therapy consists of the following:
- Epinephrine 1 mg IV/IO q3-5min
- Amiodarone 300 mg IV/IO initial bolus dose, amiodarone 150 mg IV/IO second dose OR
- Lidocaine 1st dose 1-1.5mgkg, 2nd dose 0.5-0.75mg/kg
- Flush medications with 20 mL fluid after and elevate extremity for 10-20 seconds.
- Combining medications is not recommended and may cause harm.
- Routine use of sodium bicarbonate is not recommended and may cause harm (eg, if inadequate ventilation)
- Routine use of magnesium for VF/VT is not recommended in adult patients.
Advanced Airway
Advanced airway should be established as follows:
- Endotracheal tube (ETT) or supraglottic airway (SGA)
- Waveform capnography to confirm and monitor ET tube placement
- Ventilation every 6 seconds asynchronous with compressions
- Stop CPR for no longer than 10 seconds for the placement of an advanced airway.
Return of Spontaneous Circulation
Signs of ROSC include the following:
- Pulse and blood pressure present
- Abrupt sustained increase in PETCO 2 (typically >40 mm Hg)
- Spontaneous arterial pressure waves with intra-arterial monitoring
Reversible Causes (H’s and T’s)
Reversible causes include the following:
- H’s: hypovolemia, hypoxia, H+ (acidosis), hypokalemia, hyperkalemia, hypothermia
- T’s: toxins, tamponade (cardiac), tension pneumothorax, thrombosis (pulmonary, coronary)
Updates from the 2015 guidelines:
The following are updates from the 2015 guidelines:
- Continuous measurement of arterial blood pressure and end-tidal carbon dioxide (ETCO2) can improve CPR quality during ALS resuscitation.
- Routine use of double sequential defibrillation is not recommended.
- Intravenous (IV) access is now the preferred route of administration during ACLS resuscitation. Intraosseous (IO)access is acceptable in the case that IV is not possible.
- Care after ROSC including consideration of percutaneous coronary intervention, temperature control and multimodal neuroprognostication.
- Emphasis on post cardiac arrest care including detailed assessment of physical, cognitive, and psychosocial needs.
- Importance of debriefing individuals involved in the cardiac arrest team.
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